NIIMBL is committed to supporting and accelerating the adoption of advanced manufacturing technologies. Read summaries and highlights of completed projects.
Technology Projects
December 2023
Single-use Modules for Continuous Removal of Antibody Fragments
LigaTrap Technologies, LLC, Merck & Co., Inc., MilliporeSigma/EMD Serono, North Carolina State University, Rensselaer Polytechnic Institute
November 2022
Noninvasive PAT for Aluminum-adjuvanted Vaccines
Merck & Co., Inc., Pfizer, Inc., University of Maryland Baltimore
September 2022
Specific Detection of Infected Cells Using Optical Drag-Tags in Laser Force Cytology
International Assessment of PSPT in Mice to Replace the Intracerebral-challenge Mouse Protection Test (MPT) for Whole-cell Pertussis (wP)
Developing Countries Vaccine Manufacturers Network (DCVMN)
July 2021
A Multivariate In-Line Optochemical Sensor Platform for Continuous Monitoring of Cross-Category Process Parameters and Product Attributes in Bioreactors
MilliporeSigma / EMD Serono, North Carolina State University, Pfizer, Inc.
June 2021
NIIMBL-BioPhorum Buffer Stock Blending System
Merck & Co., Inc., MilliporeSigma, Janssen Research & Development, LLC, Sanofi, GlaxoSmithKline, and others
April 2021
Software and Hardware Tools for Pharmaceutical Lyophilization Scale-up
Physical Sciences, Inc., University of Massachusetts Lowell, National Institute for Pharmaceutical Technology and Education, Inc. (NIPTE) (Uconn), Massachusetts Life Sciences Center, Purdue University, Merck & Co., Inc., Genentech
January 2021
Low-cost Production and Purification of Cytokines and Growth Factors for Cell Therapy Products
Potomac Affinity Proteins, University of Maryland College Park
December 2020
Development of a Microchip CE-HPMS Analyzer for Bioreactor Monitoring
Bristol-Myers Squibb, MilliporeSigma, North Carolina State University, University of North Carolina, Chapel Hill, 908 Devices
September 2020
Blaze Microchip System for Real-time Characterization of Intact Biopharmaceuticals
Workforce Expansion in Biomanufacturing Emerging Technologies
Montgomery County Community College, Solano College, MiraCosta College, Quincy College, Forsythe Tech, Shoreline Community College
February 2023
Modularized PAT Online Training Platform to Accelerate the Workforce Innovation in Biopharmaceuticals Manufacturing
Northeastern University, Massachusetts Institute of Technology, Genentech, Merck & Co., Inc., Janssen, Sartorius
February 2022
WORDE: A Biopharmaceutical Training Center to Promote Development of the Workforce, Outreach, Research, Diversity, and Education
Delaware State University, Merck & Co., Inc., Montgomery County Community College
January 2022
Military Service Members in Biopharma Manufacturing (MSMBM)
Texas A&M University, North Carolina Biotechnology Center, Central Carolina Community College, Durham Technology Community College, Merck & Co., Inc., and Pfizer, Inc.
March 2021
Bridging the Gap: A Biopharmaceutical Processing Workforce Development Continuum
Thomas Jefferson Institute for Bioprocessing, Montgomery County Community College, Bucks County Community College, Merck & Co., Inc.
September 2019
Reducing Door to Floor: Improving Readiness of New Hires Through cGMP Hands-on Biopharmaceutical Training
A New Generation of High-efficiency HVAC Filters that Can Be Used with Existing Infrastructure to Stop the Spread of Coronavirus Through Recirculation of Air
North Carolina State University
August 2023
Development of a Thermo-tolerant, Multidose, Egg-produced, Vector-based Coronavirus Vaccine
PATH Center for Vaccines Innovation & Access
August 2023
Development of Scalable, Thermostable, Spray Dried Vaccine Formulations Applicable for Coronavirus Vaccines
Fraunhofer USA
CARES Act Projects
October 2021
Designing a Tesk Kit Supply Chain in Response to COVID-19
North Carolina State University
October 2021
Development of a SARS-COV-2 Polyvalent Microbead Immunoassay (MIA)
New York State Department of Health (Wadsworth Center), MassBiologics of UMass Chan Medical School
March 2021
Production of N95 and Surgical Masks at the Nonwovens Institute (NWI), North Carolina State University
North Carolina State University
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